(1-3)-β-D-Glucan Detection Kit (Kinetic Chromogenic Method) developed by Xiamen Bioendo Technology Co., Ltd. has obtained EU CE certification
In April 2022, the (1-3)-β-D-Glucan Detection Kit (Kinetic Chromogenic Method) developed by Xiamen Bioendo Technology Co., Ltd. has obtained EU CE certification.
(1-3)-β-D-Glucan Detection Kit (Kinetic Chromogenic Method) is for the quantitative detection of
(1-3)-β-D-Glucan in the human serum in vitro. (1-3)-β-D-Glucan is one of the major structural
components of fungal cell walls that can lead to invasive fungal infections.
Principles of the test
The (1-3)-β-D-Glucan Detection Kit (Kinetic Chromogenic Method) measures levels of (1-3)-β-D-Glucan by kinetic chromogenic method. The assay is based upon a modification factor G pathway of the Amebocyte Lysate (AL). (1-3)-β-D-Glucan activates Factor G, the activated Factor G converts the inactive proclotting enzyme to the active clotting enzyme, which in turn cleaves pNA from the chromogenic peptide substrate. pNA is a chromophore that absorbs at 405 nm. The rate of OD increase at 405nm of the reaction solution is directly proportional to the concentration of the reaction solution (1-3)-β-D-Glucan. The concentration of (1-3)-β-D-Glucan in the reaction solution can be calculated according to the standard curve by recording the rate of change of the OD value of the reaction solution through optical detection equipment and software.
Features:
Easy to operate: two-step method;
Rapid reaction : 40min detection, sample pre-treatment: 10 minutes;
High sensitivity: chromogenic method;
Good specificity: highly specific to (1-3)-β-D-glucan;
Small sample volume: 10 μL.
Assay range: 25-1000 pg/ml
Clinical application:
Early screening, auxiliary diagnosis, guided medication, efficacy evaluation, dynamic monitoring, and disease course monitoring.
Clinical departments:
Laboratory, Hematology, Respiratory, ICU, Pediatrics, Oncology, Organ Transplantation, Infection.
Product Condition:
The sensitivity of Lyophilized Amebocyte Lysate and potency of Control Standard Endotoxin are assayed against USP Reference Standard Endotoxin. The Lyophilized Amebocyte Lysate reagent kits come with product instruction, Certificate of Analysis.
Post time: May-25-2022